Distinguished Citizens

As a start, despite: limited number of schools; inadequate books; almost nonexistence of science laboratory; far distance students must travel to get to school; diversity of background of the population, especially urban and rural students, and not so high economic status of most of the families; it is a magic that a high proportion of the students succeeded. Hence, Debre Zeit has contributed more than its fair share of successful people like Dr. Tebabu Tessema Wubetu and his friends. Some of the high achievers are highlighted below:

Patents and Publications by Inventor Dr. Admassu Abebe

Dr Admassu Abebe is born in Debre Zeit. He attended elementary and High school in Deber Zeit. He completed his high school with Distinction in Debre Zeit in 1970. He attended Addis Abeba University and graduated from school of pharmacy with great distinction. He obtained his Masters degree from England and completed his P.H.D in Industrial Pharmacy from University of Grenoble, France. Dr. Admassu Abebe is a Senior Principal Scientist at Bristol-Myers Squibb based in New York City, New York.

Dr. Admassu Abebe’s Patents and Inventions

Patent number: 9616028b
Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
Type: Grant
Filed: May 7, 2015
Date of Patent: April 11, 2017
Assignees: AstraZeneca AB, AstraZeneca UK Limited
Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
Bilayer tablet formulations
Patent number: 9050258
Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
Type: Grant
Filed: August 13, 2013
Date of Patent: June 9, 2015
Assignee: AstraZeneca AB
Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
Bilayer tablet formulations
Patent number: 8535715
Abstract: The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.
Type: Grant
Filed: November 12, 2010
Date of Patent: September 17, 2013
Assignees: Bristol-Myers Squibb Company, AstraZeneca UK Limited
Inventors: Admassu Abebe, Kyle Martin, Jatin M. Patel, Divyakant Desai, Peter Timmins
Dr. Admassu Abebe’s research Publications:
Dr. Admassu Abebe’s research while affiliated with Bristol-Myers Squibb and other places.
Number of Publications: 21
Few Examples:
Evolution of the microstructure during the process of consolidation and bonding in soft granular solids
Article
Feb 2016
Bereket Yohannes, Gonzalez, Abebe[…], Alberto M Cuitiño
The evolution of microstructure during powder compaction process was investigated using a discrete particle modeling, which accounts for particle size distribution and material properties, such as plasticity, elasticity, and inter-particle bonding. The material properties were calibrated based on powder compaction experiments and validated based on…
The role of fine particles on compaction and tensile strength of pharmaceutical powders
Article
Apr 2015
Bereket Yohannes, Gonzalez, Abebe[…], Alberto M Cuitiño
The role of fine particles on compaction of powders and the resultant compact was studied experimentally. Samples of powders were prepared by successively removing fine particles from microcrystalline cellulose and lactose monohydrate powders. This method of preparing samples is unique compared to previous studies on particle size distribution, and…
Review of Bilayer Tablet Technology.
Article
Dec 2013
Admassu Abebe, Ilgaz Akseli, Omar Sprockel[…], Alberto M Cuitiño
Therapeutic strategies based on oral delivery of bilayer (and multilayer) tablets is gaining more acceptance among brand and generic products due to a confluence of factors including advanced delivery strategies, patient compliance and combination therapy. Successful manufacturing of these ever more complex systems needs to overcome a series of cha…
Axial strength test for round flat faced versus capsule shaped bilayer tablets
Article
Nov 2013
Jason Franck, Admassu Abebe, Rekha Keluskar[…], Howard Stamato
Abstract There has been increasing interest in fixed dose combination (FDC) therapy. Multi-layer tablets are a popular choice among various technologies to deliver FDCs. In most cases, round flat faced tooling is used in testing tablets as they have the simplest geometry. However, shaped tooling is more common for commercial products and may have a…
The Use of Foam in High Shear Wet Granulation: Effect of Scale up On Granules Quality Attributes
Conference Paper
Nov 2010
Niranjan Kottala, Admassu Abebe, Faranak Nikfar[…], Robert Jerzewski
High shear wet granulation is a common pharmaceutical unit operation for forming agglomerates. The API under study offered challenges during processing due to its low bulk density, low particle size, and its adhesive nature when in contact with water. To address the above challenges a new granulation process was employed whereby liquid binders are…

Patents by Inventor Dr. Taddesse Gebregiorgis

Dr. Taddesse was born and raised in Debre Zeit. He is one of the graduates of Prince Tenagework High school in 1970 in Debre Zeit. His educational background includes: Bachelor of Science (BS) Organic Chemistry, The American University in Cairo, Egypt; PH.D Polymer Chemistry University of Essex, England; and Post Doctoral Fellowship Polymer Chemistry University of Grenoble, France
Dr. Taddesse was a Senior Research Associate with a demonstrated history of working in the chemicals industry. Skilled in Research and Development (R&D), Chemistry, Life Sciences, Polymers, and Organic Chemistry.
Patents and Inventions:
Anti-corrosion electrocoat
Patent number: 10358735
Abstract: The present disclosure relates to the application of anti-corrosion coatings for a ferrous substrate. The first coating applied to the ferrous substrate is an electrocoat composition comprising electrically conductive pigments. A dried a cured coating layer of the first electrocoat composition provides the basis for a second electrocoat composition.
Type: Grant
Filed: May 23, 2012
Date of Patent: July 23, 2019
Assignee: Axalta Coating Systems IP Co., LLC
Inventor: Taddesse Gebregiorgis
Method for using 3-coat-1-bake waterborne coating composition
Patent number: 9903021
Abstract: Disclosed herein is a method to apply waterborne primer, basecoat and clearcoat compositions in a wet-on-wet manner followed by the curing of all three applied compositions to form a durable protective coating on a substrate. The primer composition comprises (meth)acrylic latex, polyurethane resin, melamine and, optionally, polyesters.
Type: Grant
Filed: December 29, 2009
Date of Patent: February 27, 2018
Assignee: AXALTA COATINGS SYSTEMS IP CO., LLC
Inventors: Taddesse Gebregiorgis, Donald Albert Paquet, Jr.
Organic solvent free pigment dispersant for waterborne electrocoating
Patent number: 8236157
Abstract: A pigment dispersing resin is disclosed along with pigment dispersion, electrodepositable coating compositions using the pigment dispersing resin, and methods for applying the electrodepositable coating composition. The pigment dispersing resin consists essentially of the carboxylic acid salt of an aminated bisphenol epoxy resin and an alkoxylated styrenated phenol. Pigment dispersions made from the dispersing resin are especially useful for forming low or no volatile organic content electrocoating baths.
Type: Grant
Filed: December 12, 2008
Date of Patent: August 7, 2012
Assignee: E I du Pont de Nemours and Company
Inventor: Taddesse Gebregiorgis
Cathodic electrodeposited coatings having high lubricity
Patent number: 6114040
Abstract: Self-lubricating is provided for cathodic electrodeposited coatings by including in the coating bath fine particles of polytetrafluoroethylene that have been milled with a cationic polyepoxide resin.
Type: Grant
Filed: September 9, 1998
Date of Patent: September 5, 2000
Assignee: E. I. du Pont de Nemours and Company
Inventors: Taddesse Gebregiorgis, Kathleen S. Shields, John Joseph Vincent
Pigment dispersant for cathodic electrocoating compositions
Patent number: 5324756
Abstract: A pigment dispersant that is useful in a cathodic electrocoating composition is prepared by bringing into contact the following compounds: a cyclic alkylene urea amine, a polyepoxide and a dialkanol amine; this pigment dispersant has an advantage of allowing for the high pigment to binder ratios and minimizes the volatile organic content (VOC) in the electrocoating composition.
Type: Grant
Filed: May 5, 1993
Date of Patent: June 28, 1994
Assignee: E. I. Du Pont de Nemours and Company
Inventor: Taddesse Gebregiorgis
Imidazoline amine-epoxy adduct as a pigment dispersant
Patent number: 5128393
Abstract: A pigment dispersant useful in cathodic electrocoat compositions is disclosed. The pigment dispersant is the reaction product of an organic monoepoxide or polyepoxide with a primary amine containing an imidazoline moiety. This pigment dispersant allows the maximazation of pigment to binder ratios and the minimization of volatile organic content (VOC) in electrocoat baths.
Type: Grant
Filed: June 11, 1991
Date of Patent: July 7, 1992
Assignee: E. I. Du Pont de Nemours and Company
Inventors: Stephen C. Peng, Taddesse Gebregiorgis
Pigment dispersant resin: reaction product of imidazoline and alkylene carbonate adduct and a half blocked diisocyanate
Patent number: 5116903
Abstract: A pigment dispersant that is useful in a cathodic electrocoating composition is prepared by bringing into contact compound (i), an alkylene carbonate, with a compound (ii) of the structure: ##STR1## where R is and alkyl group having 8-24 carbon atoms, and bringing the resulting reaction product of (i) and (ii) into contact with a half blocked organic diisocyanate; this pigment dispersant has an advantage of allowing for the maximization of pigment to binder ratios and the minimization of volatile organic content (VOC) in electrocoating compositions.
Type: Grant
Filed: April 5, 1991
Date of Patent: May 26, 1992
Assignee: E. I. Du Pont de Nemours & Co.
Inventor: Taddesse Gebregiorgis
Pigment dispersant resin: reaction product of imidazoline amine and alkylene carbonate
Patent number: 4946507
Abstract: A pigment dispersant useful in cathodic electrocoat compositions is disclosed. This pigment dispersant is the reaction product of alkylene carbonate and a primary amine containing an imidazoline moiety. This pigment dispersant allows the maximazation of pigment to binder ratios and the minimization of volatile organic content (VOC) in electrocoat baths.
Type: Grant
Filed: July 12, 1989
Date of Patent: August 7, 1990
Assignee: E. I. Du Pont de Nemours and Company
Inventors: Stephen C. Peng, Taddesse Gebregiorgis

Book and Publications by Professor Dr. Brook Lemma Mamaru

Dr. Brook Lemma Mamaru attended Atse Libne Dingle elementary school and up to grade 10 high school in Debre Zeit. He graduated in 1970 from Shimeles Habte high school in Addis Ababa. He attended Addis Abeba University and Obtained a BSc in Biology and MSc in Zoology with special emphasis on veterinary parasitology. He completed his PhD in Germany in Freshwater Ecology with special emphasis on the food web analysis from nutrients all the way up to the predatory fishes for the purpose of lake management. He is currently a Professor in College of Natural Science.

Books By Professor Brook Lemma Mamaru

Introduction to lake ecology, aquaculture, and fisheries in Ethiopia by Brook Lemma First published in 2008.

Research Publications by Professor Dr. Brook Lemma Mamaru

Summary of Research publications on Research Gate:
Number of Publications: 36
Reads: 14,497
Citations: 382
Few Examples:
Assessment of spatio-temporal variations of selected water quality parameters of Lake Ziway, Ethiopia using multivariate techniques
Mar 2022
Dessie Tibebe, Feleke Zewge, Brook lemma Mamaru, Yezbie Kassa
Excess agrochemicals input from agricultural activities and industrial effluent around Lake Ziway catchment can pose a serious threat on the lake ecosystem. Lake Ziway is a shallow freshwater lake found in the northern part of the Ethiopian Rift Valley. It is characterized as semi-arid to sub-humid type of climate. Expansions of the flower industry…
Food and Feeding Biology of Nile Tilapia (Oreochromis niloticus) in Lake Langeno, Ethiopia
Jan 2022
Mathewos Temesgen, Abebe Getahun, Brook lemma Mamaru, Geert P. J. Janssens
This study aimed to investigate the natural feeding behavior of Nile tilapia in Lake Langeno, Ethiopia, with emphasis on potential spatial, size and seasonal effects on ingested food items. This study of the food and feeding biology of O. niloticus in Lake Langeno, Ethiopia, was conducted from March 2016to February 2017. Fish samples were collected.
Evaluation of Tannery Wastewater Treatment by Integrating Vesicular Basalt With Local Plant Species in a Constructed Wetland System
Oct 2021
Agegnehu Alemu, Nigus Gabbiye Habtu, Brook lemma Mamaru
Tannery wastewater is composed of a complex mixture of organic and inorganic components from various processes that can critically pollute the environment, especially water bodies if discharged without treatment. In this study, integrated vesicular basalt rock and local plant species were used to establish a horizontal subsurface flow constructed w…
Livelihood Functions of Capture Fisheries in Sub-Saharan Africa: Food Security, Nutritional, and Economic Implications
Article
Full-text available
Jan 2019
Mathewos Temesgen, Abebe Getahun, Brook lemma Mamaru
The objective of this review was to investigate the livelihood functions of capture fisheries (food security, nutritional, and economic implications) in Sub-Saharan Africa. Published and unpublished sources were used to obtain appropriate data. Capture fishery is the most important livelihood activity in the region. The contribution of capture fish…
Low-Cost Stormwater Filtration System to Improve Urban Water Quality: The Case of Addis Ababa, Ethiopia

Dagnachew Adugna, Larissa Larsen, Brook Lemma, Geremew Sahilu
Journal of Water Resource and Protection Vol.9 No.6，May 27, 2017
DOI: 10.4236/jwarp.2017.96046 1,271 Downloads 2,318 Views Citations
This article belongs to the Special Issue on Urban Water Systems and Challenges
Brook Lemma (National Consultant) (2012): Report on the Value Chain (Marketing) Assessment of the Fishery Sector in Ethiopia. Publisher: Food and Agriculture Organization Sub-Regional Office for Eastern Africa (FAO/SFE), Addis Ababa. 131 pp.
Brook Lemma (National Consultant) (2013): The Value of African Fisheries: Contribution of Ethiopian Fisheries to the GDP. A report submitted to Food and Agriculture Organization of the United Nation (FAO), Rome.
Brook Lemma (2013): Environmental and Social Impact Assessment of the Rivers and Lakes of the Ethiopian Rift Valley. A scientific researching consultant report on the fisheries, water quality and social impacts on the rift lakes and rivers and submitted to the Environmental Resources Management, United Kingdom (ERM) and ESSD, Addis Ababa.

Research Publication by Dr. Jonathan T. Wubetu

The immunology of solid organ transplantation:
By Christopher Brown, Marc Clancy, Jonathan T. Wubetu
Anaesthesia and Intensive Care Medicine, J Christopher Brown, Marc Clancy, Jonathan T. Wubetu | Anaesthesia and Intensive Care Medicine, July 22, 2021
3D bioengineered systems for tissue engineering cancer research:
By J Wubetu, JM Rios de la Rosa, A Tirella*
Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK, June 2017
Conference: TERMIS EU Chapter At: Switzerland, Davos
Affiliation: The University of Manchester

Case report

Living donor kidney transplant following nephrectomy for renal artery stenosis with arterial reconstruction and viability assessment using ex vivo normothermic perfusion
http://orcid.org/0000-0003-4199-3099

Robert Pearson, Jonathan Wubetu, Andrew Jackson, and David Kingsmore

Dr. Habtu Assefa

Dr. Habtu Assefa is a graduate of Prince Tenagnework High School. Dr. Habtu obtained his PhD from Wageningen University in the Netherlands, and both his MS and BS degrees from the University of Florida, Gainesville, in the USA.
Dr. Habtu has a background in agriculture with more than 35 years of experience from research, development and professional work. He served as a Deputy Country Director (DCD) and Project Coordinator in the Sasakawa Africa Association – SG2000 Ethiopia. Dr. Habtu coordinated the BMGF-supported project ‘Strengthening Agriculture Extension Delivery in Ethiopia’ and Digital Green Scale up project. As a DCD he was also responsible for supervising several donor supported projects in SAA/SG2000 Ethiopia. He was also the Coordinator and Advisor for the SIDA-Amhara Rural Development Program, in on-farm research and agricultural and natural resource management.
He served in various capacities at the Ethiopian Institute of Agricultural Research, based at Adama, for more than 22 years in the areas of agronomy and plant pathology research. His research focused on pulses, fruit crops, and vegetables. He developed management practices for the control of diseases and crop management for improving yield. As a result, he has developed improved technologies and practices, published and edited a number of publications. Through research and professional work, he has developed extensive experience and capacity in preparing research strategic plans, methodology for on-farm research, training and monitor and evaluate research and development projects. (source: Dr. Habtu Assefa – HOMEGROWN VISION)